What is BPC 157? Our Buyer’s Guide  

Bpc157 is a pentadecapeptide and a peptide, i.e. a short sequence of amino acids. Amino acids can be found naturally in the body, however, this one is produced synthetically. 

In detail, this peptide is a sequence of 98 hydrogen, 62 carbon, 22 oxygen, and 16 nitrogen atoms – put together, the nitty-gritty chain is spelled out with the following molecular formula:

C62-H98-N16-O22

So much for the fancy formula, but what’s with the name? If you’re curious, the acronym in bpc peptide stands for “Body Protecting Compound”. The body naturally produces BPCs in the gut and stomach which serve to protect the organs from the unwanted activity and helps them heal. The great news is that wherever you put these compounds in the body, they will bring about regenerative properties.

How Does BPC 157 Work?

The bpc 157 peptide triggers the formation of new blood vessels, promoting tendon growth and muscle healing. This is a natural process called angiogenesis, used by the body to help it heal from cuts, wounds, and any damage from trauma. 

Examples can be found all over the body. Studies, for example one conducted by Xiaoming et al, show that the compound can help reduce Inflammatory Bowel Disease by helping the inflamed lining of the gut heal up. Other studies from the Journal of Orthopedaic Research as well as Chang et al show that bpc-157 causes tendon cells to heal and grow because they increase growth signaling molecules, block growth-inhibiting effects from other molecules, and reduce inflammation in the body. The brain is an organ also positively impacted by the substance – research shows how it regulates the production of dopamine and serotonin, helping people deal with seizures, depression, and pain.

BPC 157: Benefits and Side Effects

With a lot of potential promise, let’s examine both the benefits and bpc 157 side effects. When you do your research, you will notice a lot of interesting benefits of using bpc 157. However, any substance that you take, no matter what it is, brings about a biological cost and benefit. There is no perfect solution in biology, and the human body is a complicated thing, so let’s consider the evidence surrounding the use of bpc 157 tablets and powders.

Benefits

The Brain and nervous system

Exciting studies on animals from the journal Regulatory Peptides found that BPC 157 injections help to reduce brain damage, the physical effects of trauma on the brain and ultimately helped the animals stay alive for longer. In recent research undertaken on rats, the product results in an overall decrease of traumatic nerve injury and has even been found to positively affect the mood of such animals. Scientists have even likened a comparable effect to conventional antidepressants.

Cuts, Burns and Broken Bones

Research from the Journal of Physiology-Paris has found that the compound is a potentially useful therapeutic agent for trauma when tested using different experimental treatments on animals. Experimental models, mainly done on rats, show that the substance turbocharges the healing process in tissues and bones. Other studies on rabbits note how it can be used to heal broken bones, and with our DNA makeup not too far away from either animal, there is a promise for humans too.

Pain relief

Studies have found that the effects of taking bpc 157 are mild and beneficial. Although it does not provide pain relief comparable to substances such as morphine or aspirin, the substance has been found to decrease the susceptibility of pain in animals, particularly the animals were pinched or subjected to unpleasant stimuli.

Regulation and Balance of Blood Pressure

Although studies have not yet been carried out on humans, anecdotal accounts in various bpc 157 reviews point towards the benefits of decreasing blood pressure, so what’s the deal there? Recent bpc 157 results in animal testing studies show that it does in fact stabilize animal blood pressure. Animals given a chemically induced high blood pressure were given injections, and findings show that these injections decreased blood pressure overall. The results are something to think about, especially how the tested animals share 97.5% of the human genome.

Balancing levels of potassium

When the body has a level of potassium that is too high and the blood, this can cause fatigue, muscle weakness, and irregularities in the heart that can lead to death. Fortunately, studies such as those carried out in the journal Regulatory Peptides show that animals given injections of BPC 157 had a better chance of survival when subjected to unhealthy doses of potassium in the blood. The injections significantly prevented animals from dying, whereas those that did not receive the injection died in half an hour’s time.

Intoxicating Effects of Drugs

Drugs are often highly intoxicating for the human body. Bpc 157 administered in scientific testing helped counteract chemical imbalances in animals after they were subjected to amphetamines. Similar studies have been carried out on animals given morphine, where bpc 157 decreased the intoxicating effects. Doctors around the globe often struggle with intoxicating effects when treating patients as the effects can often lead to greater problems down the line.

Side Effects

Every human body is different, and every taken substance will produce an effect. So it is very important to consider the various side-effects of this peptide and how they may impact your health. 

Common side effects include the following:

●     Weight gain (not ideal for weight loss)

●     Suppression of satiety

●     Liver toxicity

●     Cancerous cell growth

●     Blood pressure change

●     Dizziness and fatigue

●     Heart palpitations

●     Toxins passing to foetuses

It can be very beneficial for the body to grow new blood vessels, treat injuries, and experience pain relief, however, there can be dangerous risks, especially associated with cancer. Although no studies have yet suggested that BPC 157 increases a man’s risk of cancer, it is important to consider. Some studies have even shown that BPC 157 can be effective in a therapeutic manner for cancer patients who experience wasting of muscles. However, the risk is perceived to be largest when there is already cancer in the body, as increased blood vessel growth can feed a tumor much faster, causing them to spread more easily.

We highly recommend speaking to your doctor before taking any peptide. Side effects are often the result of improper use or dosage, so it’s best not to risk it and consider the best practices for taking the product.

Dosage and Cycling

As of yet, there are no peer reviews of trials that have examined bpc 157 dosage on human beings. In addition, the Food and Drug Administration has not approved the substance for treating conditions in humans, nor have they prescribed guidelines on recommended doses. Most of what you will hear about doses from manufacturers is based largely on unscientific trials.

However, even though there are no clinical trial results for humans, a maximal dose of around 600 µg for a 132-pound human is a good starting point. This data, which can be scaled up or down depending on your weight, comes from the best of those practices on other animals that are found in studies from the likes of Kang et al. and others. These are numbers based on what you might take in a single dose.

It is important that you consider the implications of taking the substance because scaling doesn’t often work well between different species. For instance, some people may take around 250 µg a day for pain relief, whereas others may take much less. The aforementioned studies were also carried out using injections, rather than administering the drug orally, which is the common practice for humans. Some people do inject the substance, but it is uncommon.

As with any substance, to take it at your own risk. The doses discussed are guidelines, but they are not 100% scientific. As with any information you read, question its authenticity and always talk to your doctor before taking BCP 157.

Inject BPC 157 or Take It Orally?

What’s the best way of administering this substance? Do you go for injections or bpc 157 nasal spray? Some people even use a bpc 157 patch. The most important thing to note is that BBC 157 will work regardless of the method you use.

Just like is carried out in the majority of scientific studies, you can inject the substance subcutaneously, i.e. application just under the skin. This is a relatively easy and pain-free method compared to intramuscular injection, whereby you need to start the needle right into muscle tissue. Both of these methods work best when applied as close to an area of pain as possible if you are looking to use the substance for pain relief. If you are okay with needles, make sure you pension the area of skin first that the needle can enter the body more easily. After injecting, make sure that you clean the area thoroughly with an alcohol-based swab, to reduce any chance of infection.

If you’re into peptides bodybuilding but can’t stand the sight of needles, a bpc 157 oral administration is possible. You can either take a capsule or spray a thin mist of the peptide into your mouth. We recommend holding the peptide in your mouth for at least a hundred seconds before swallowing.

Limitations and Caveats  

If you research bpc 157 capsules and the science behind them, do bear in mind that clinical trials on humans are rare, if not very small, and confined to experimental settings. The studies that we have discussed are all administered on animals in laboratories, and although such information is certainly valuable, animals are not humans.

While it certainly isn’t a shock to see the outcomes of this product in laboratory settings, it is worth noting that research on humans is currently in the pipeline and we can’t expect to see mass clinical trials conducted any time soon. Any studies or evidence you read regarding bpc 157 and animals can only be scaled up to humans to a certain degree.

Feedback From Real Users

When you look at any bpc 157 review, and read pieces on “tb 500 vs bpc 157” or related matters, it’s important to bear in mind that the opinions are expressed solely on an anecdotal level and should not be taken as hard scientific fact. You certainly do not endorse any specific treatment, product, service, or method that hasn’t been studied extensively by scientists.

No matter how much you would like to believe it, the hard-line is that a user’s experience never counts as medical advice. This is why you should never refrain from asking a doctor or healthcare professional when taking any substance for yourself. Of course, there are a multitude of real-life sources out there that can certainly give you a good overview of bpc 157, but it should never be taken as gospel.

That said, the vast majority of users are positive about the product’s effects. If you look at various professional opinions on muscle forums, users report that the product helps with their soreness, injuries, tendinitis, inflammation, and many other ailments.

However, some people report no significant benefit from using the product. Others are also wary of the high costs involved, but prices do vary depending on sources. 

Many are also confused about how to use it and the recommended dose. In an extensive review of forums, we found some people reported getting unpleasant side-effects, but it did not make up the majority of reviews.

It is important to note that the number of users have raised issues about companies and mislabelling peptides but are cheaper to produce as bpc 157. This is a worthy concern, and we urge you to only choose from the most reputable companies if you are to purchase the product yourself. Not everything on your average bpc 157 buy online page does exactly what it says on the tin.

Concluding Remarks          

Now that you’ve read all about the peptide bpc-157, you may be wondering why this natural substance, similar to what is found in natural gastric juices, isn’t on the market yet. The key is that it can’t be patented at all because it is a completely natural gastric juice peptide. Large pharmaceutical companies aren’t able to make a lot of money because their investments are not protected and anybody can make the product. The result is that it slows down approval from the Food and Drug Administration. It even prevents this organization from considering it to be sold for human use, although things may change over time.

Unlike a variety of other peptides, the good news is that BPC 157 is not bound by respected sports bodies such as WADA. This means that if you’re an athlete looking to reap the benefits, bpc-157 is legal to take before sporting events, for the time being at least. There is no way of knowing for sure what the future will bring, but it is unlikely to be banned for many years to come. In the meantime, no significant adverse effects have been found in any short-term studies in humans.

In summation, there are a number of well-documented bpc 157 benefits, from regenerative properties to healing tissues and protecting organs. Although more research needs to be done, the product works in a variety of different animals, and many thousands of users around the world swear by bpc 157 for helping them build muscle and rid themselves of various ailments.

Article compiled using information from the following sources:

1. https://www.ingentaconnect.com/content/ben/cpd/2013/00000019/00000001/art00005
2. https://onlinelibrary.wiley.com/doi/abs/10.1016/S0736-0266(03)00110-4
3. https://journals.physiology.org/doi/full/10.1152/japplphysiol.00945.2010
4. https://pubmed.ncbi.nlm.nih.gov/15840402/
5. https://www.sciencedirect.com/science/article/abs/pii/S0167011509002341
6. https://www.sciencedirect.com/science/article/abs/pii/S0167011509002274
7. https://www.sciencedirect.com/science/article/abs/pii/S0928425797894806
8. https://link.springer.com/article/10.1007/BF02659088
9. https://www.sciencedirect.com/science/article/abs/pii/S0167011513000086
10. https://pubmed.ncbi.nlm.nih.gov/11978191/
11. https://www.sciencedirect.com/science/article/pii/S0968089617310222
12. https://pubmed.ncbi.nlm.nih.gov/29898649/
13. https://josr-online.biomedcentral.com/articles/10.1186/s13018-019-1242-6

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Peptides work in a variety of different ways on the body, and in the case of cjc 1295, this product acts as a hormone secretagogue, causing the body to release Growth hormone via the pituitary gland.

Human Growth Hormone (HGH) produces a lot of powerful effects including an increase in muscle mass, energy, and a boost in metabolism, but it can be dangerous to introduce the hormone directly into the body. Rather than do this, a peptide such as CJC 1295 safely triggers your body to produce the hormone on its own, in a natural manner.

The research was initially carried out on the peptide because it was thought that it could treat certain diseases, but professional athletes have soon discovered its performance-enhancing effects. It has gained an appeal amongst athletes and the athletic community worldwide, helping synthesize protein and cause more muscle tissue to grow. It is also largely appealing as an anti-aging peptide, typically combined with other peptides such as Ipamorelin, although the latter has a shorter half-life, smaller period of action and there are some ipamorelin side effects.

Two Types of CJC-1295: What are They?

Interestingly, there are actually two different types of CJC 1295 (Ipamorelin). To understand, you need to look at the hypothalamus where growth hormone-releasing hormone (GHRH) is produced. The release of GHRH causes HGH to be released from the pituitary gland. The half-life of GHRH is relatively short and it is removed from the blood very quickly.

Manufacturers first created a peptide known as Sermorelin with a half-life of 30 minutes called CJC-1295. However, this was modified in the future by adding a Drug Affinity Complex (DAC), which helps increase the overall half-life by 8 days – this is what’s known as cjc dac.

What is Ipamorelin?             

Ipamorelin is a peptide made up of 5 amino acid chains that are often used in combination with CJC 1295 to increase HGH levels. The two substances are very similar and used in tandem to produce more HGH via the pituitary gland. Ipamorelin was the first selective growth hormone secretagogue to be developed. What this means is that Ipamorelin mimics the action of ghrelin in the body and via this process triggers the release of HGH. 

Most of the time, hormones trigger a number of other hormones in the body, leading to unwanted side effects, but Ipamorelin only triggers HGH release.

Why Combine CJC-1295 and Ipamorelin?

You may have read about cjc 1295 ipamorelin benefits online, and the two products are often combined together for better use. Ipamorelin generates a very similar increase in HGH, but without suppressing satiety or increasing levels of acetylcholine, cortisol, prolactin or aldosterone. The result is healthy muscle generation in a way that is well tolerated by the body.

CJC-1295 – Benefits and Buyer’s Guide

Although the vast majority of cjc1295 studies are on animals, there is ample research on the compound’s effect on humans too. However, most large-scale studies are pending. Most people take the product either for its anti-aging properties or because it generates an increase in muscle mass, but there are other great things it can do too. Let’s take a look at some of the main benefits:.

●     Studies from the likes of Svensson et al. show that CJC 1295 can increase bone density and bone mineral content. Testing was carried out on rats in experimental settings – the group of rats that had the peptide injected experienced four-fold increases in bone density.

●    The peptide can offset HGH deficiency in humans.

●    The Journal of Hormone Research in Paediatrics carried out some interesting studies on GHG, linking it to accelerated body fat loss. Obese participants that had the peptide administered to them experienced accelerated fat loss over time.

●     Your metabolism and energy will increase, helping you last longer and giving you more energy on the whole. This can actually help you decrease weight over time.

●     As a result of increased levels of HGH, your injuries and wounds will heal faster and better than normal.

●     It’s difficult to build lean muscle mass, especially as you get older. Studies such as those carried out by Andersen et al. have discussed the reasons behind growth hormone secretagogue increasing muscle mass. CJC 1295 helps you put on lean muscle with very few side effects to the body.

CJC-1295 Side Effects

Research into cjc peptide reveals surprisingly few side effects and adverse reactions in both human and animal testing. If you consider that the body requires amino acids in the first place, it is unlikely that further introduction of a small amount of them will adversely affect the average user. 

However, biology is complicated and every human body is different, so there are always some side effects. When looking at various CJC-1295 reviews, you’ll find that the most common side effects include redness, irritation, pain, and swelling, yet these are also common symptoms of improper injection practice. 

In addition, some of the most common effects are:

●     Pain around the area of injection

●     There like symptoms

●     Touch insensitivity

●     Nauseous feelings

●     Irritation of the skin around the injection site

If you take CJC-1295 and notice some serious medical conditions arise, you should stop taking the product and contact your doctor. Don’t risk and ignore it – seek medical attention immediately. 

CJC-1295 / Iparmorelin: Dosage, Storing and Other Considerations

Although there is a lack of concrete guidelines on how to take the product, there are definitely some wrong ways to do it, and it is important to administer cjc-1295 correctly. We recommend injecting the product into your body, so let’s find out more about how to do this.

Best Way to Use CJC-1295

It can be daunting at first, but injection is best done subcutaneously, i.e. in a fatty part of your body. Some of the best and easiest places to inject include the waist, upper thigh, or back. Make sure to keep things as sterile as possible, and always clean the site before and after with an alcohol-based swab to prevent any risk of infection. Always mix your best peptides with sterilized water before drawing them into a syringe.

Dosage

A typical dose of the peptide is around 300 mcg per day, which can be administered once or twice a day in doses ranging from 250 to 100 mcg. It’s even possible to go as far as 500 mcg in one dose.

Your dosage cycle will vary based on your general activity. For those who exercise frequently or are involved in bodybuilding, a typical cycle is three months, but you can also push up to 16 weeks to get the maximum benefits. If you’re just starting out,  go for a much smaller cycle between two and four weeks. If you feel as though your body can handle it, you can make incremental increases.

The great thing about cjc 1295 administration is that you can take it whenever you want in the day, although injecting when you’re on an empty stomach will bring about the best results. We recommend injecting in the evening (as this is when the body naturally tends to secrete HGH) around 20 minutes before you eat or drink. Always speak with your doctor before starting your cjc 1295 no dac cycle.

Many people take cjc 1295 in combination with DAC, another peptide that results in overall greater peptide bonding. For those who want to use cjc 1295 dac together, your cjc 1295 dac dosage cycle will require a smaller dose because of the shorter half-life of DAC. It is important to check in on your body and assess how you feel. 

Storing and Shelf Life

With common freeze-dried peptides such as CJC-1295, you can store them at room temperature in their initial packaging for up to one month, sometimes even longer. If you’re planning on long term storage, they will last in your fridge at 4 °C or colder for several months. Always try and keep them out of natural sunlight or away from intense light as this can damage the compound. For best results with long term storage, if you can get low enough freezing temperatures, store your peptides below -20 °C. 

Forms Available 

We’ve talked about injection as this is the most common and effective form, but there are other ways too. If you’re not so keen on sticking needles in, it is possible to consume the peptide orally. It results in slightly lower absorption rates, however, if you keep it under your tongue for as long as you can, this will massively up the absorption rate to around 95%.

CJC-1295  Safety Precautions

When using cjc 1295 and ipamorelin, we recommend taking a break of three to six months in order for your pituitary gland to recover and not be overstimulated. These “peptide holidays” can minimize your risk of HGH resistance.

If you take too much of the peptide without a break, antibodies can bind excessively to inactivate HGH or you may experience something called down-regulation, where there will be fewer HGH receptors found on tissues. Although these are mild concerns and no long-term studies have shown anything other than theoretical concerns, it’s better to be safe than sorry.

It’s important to point out that cjc 1295 with or without dac is not suitable for pregnant or breastfeeding women. If in doubt, always ask your local physician or medical practitioner for advice before taking this peptide.

CJC-1295 Results: What to Expect and How Soon?  

Having discussed cjc 1295 dosage, when are you likely to see results after taking the product? After all, what is cjc good for if it doesn’t bring results? Results are dependent on the individual aspects that make up your physiology, including your lifestyle, age, genetics, and immune system functioning. It will likely take you a few weeks before you notice any significant difference. Although not a quick-fix solution, it’s not super slow either. 

Take a look below at what an average user might expect to experience over time:

CJC 1295: Before and After Results

Here are some photos of the sportsmens claimed to use peptides, one of them is CJC 1295. Just take a look at the photos:

Concluding Remarks          

We hope that our cjc 1295/ipamorelin guide has illustrated the pros and cons to help inform your future decisions. There are a number of benefits, mostly the acquisition of lean muscle mass and various anti-aging properties. As you read this in 2020, a lot of studies are happening on ipamorelin peptide and cjc 1295 that may contribute further to the reliability of findings.

It is always important to understand the tradeoffs and consider the side effects, be sure to research extensively before administering any peptide yourself. Always consult with a doctor or healthcare professional before taking CJC-1295, because although there are relatively few side effects, not every human body reacts the same way. All the best!

Article compiled using information from the following trusted sources:

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What is PEG-MGF?

PEG-MGF is derived from IGF-1 and it stimulates myoblasts division which in turn makes the muscle fuse and mature. This is a necessary process for adult muscle growth. Mechano Growth Factor (MGF) is a peptide, derived from a different sequence of IGF-1. It plays a major role in childhood development and has a significant function in anabolic activities throughout adulthood.

It’s produced in the liver and it breaks down within 5-7 minutes. That is why scientists have added a compound into MGF to modify it. This increases the half-life of MGF up to several days and the modified compound is called PEG-MGF.

How PEG-MGF Work?

The most important work of PEG-MGF is that it helps in faster recovery and healing of muscles and helps the cells to grow and get bigger. They bind to the receptors and help in the recovery of damaged tissues. Their work is to generate new muscle growth on top of an existing layer of muscle. Not only does it help bodybuilders but also helps to cure age-related muscle loss disorders. One of the benefits of PEG-MGF is that you can grow new muscles in any area that you desire.

The Distinction between MGF and PEG-MGF

Many people come across the ghrp 2 vs ghrp 6 ​dilemma. What is the distinction between these two? The main difference between IGF-1 derived PEG-MGF and MGF is that the latter stimulates myoblasts through the stimulation of different receptors. Whereas, PEG-MGF increases the muscle stem cell count so that many more cells fuse and become a part of adult muscles.

What are the benefits of PEG-MGF?

Our PEM-MGF review will help you understand all the benefits of this peptide. Recently peg-mgf has gained a lot of popularity due to its various benefits. Not only does it help in adding new muscle growth but it also helps cure few muscle disorders. As it helps in strengthening bones too you can also use it for bone-related diseases. 

Here are a few benefits of PEG-MGF:

• Promotion Of  Skeletal Muscle – Research has found that when MGF is injected directly into the muscle it helps to protect it. In doing so it decreases the expression of some specific inflammatory hormones and lowers the oxidation stress.
• Anti-aging Benefits and Fat Metabolism – This happens when MGF stimulates the IGF-1 receptors which lead to decrease aging and an increase in lean body mass. Along with that, it poses a significant role in fat metabolism.
• Heart Muscle Repair – MGF inhibits apoptosis that cardiac muscle cells go through after hypoxia. MGF helps in the recruitment of the cardiac stem cells to the injured site and it may help to heal the heart after a heart attack.

PEG-MGF Side Effects

Indeed, there are many positive effects associated with PEG MGF peptide based on scientific research and animal testing. But it is important to keep in mind that there have been some records of unfavorable effects related to PEG-MGF. 

These negative PEG-MGF side effects are

• One of the negative effects of PEG-MGF found after animal testing is Hypoglycemia or ‘ low blood sugar’. As PEG-MGF increases the efficiency of cellular functionality, blood sugar achieves its functional goal too quickly thus resulting in Hypoglycemia.
• Swelling of the extremities which mean limbs, arms, and legs (particularly hands and feet)
• The blood pressure of the body drops, in some cases, when you take this peptide.
• It is also associated with irregular cardiovascular activities. So much so that it can even lead to cardiac arrest in some cases.

How to take PEG-MGF?

The most preferable way to take PEG-MGF is to inject it intramuscularly. But due to its long half-life, you can also inject it under the skin into the fat tissues (belly, buttocks, thighs). Even if you inject it under the skin it would still make its way to the receptors present on the muscle cells and be as effective.

PEG-MGF Dosage and Cycle

Athletes who use it for hypertrophy (increase in the volume of an organ or tissue) and recovery tend to do so once daily. PEG-MGF dosage of 200 to 500 µg on off days while a dose of 100 to 200 µg on post work out intervals are most common. It is injected subcutaneously.

If you decided to take capsulated PEG MGF, we recommend you to start with 3 capsules per day.

As for the recommended cycle, it is commonly incorporated for a maximum of four weeks.

Results of PEG-MGF

PEG-MGF results are quite fascinating. It produces new muscle fibers and also helps to stimulate growth in affected areas. It may also promote the retention of nitrogen in muscle fibers while increasing protein synthesis.

This peptide can be very helpful to bodybuilders as they help in creating new muscle tissues, which in turn would increase the total muscle mass of the body.

Final Thoughts

And that’s about it. As you might have already understood that along with bodybuilding peptide PEG-MGF also helps to cure certain muscle and bone-related disorders. It’s always wise to know every detail about the product that you intend to use. Even better to consult a doctor about it. Hope this review was helpful to you and answered all your questions. And If you still have any, feel free to ask in the comment section below. We will be happy to get back to you.

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What is Andarine?

Andarine or S-4 is one of the newly developed SARMS. It’s known for its properties to heal osteoporosis, muscle wasting, and benign prostatic hypertrophy. When compared, it is found that S-4 SARM is stronger than Ostarine but weaker than LGD 4033.

Andarine is an investigational SARM but the Phase I Human trial shows very promising results. It is often considered the most potent SARM in the market.

Mechanism of Andarine (S-4)

The process in which S4 SARM works is pretty similar to that of a steroid. The only difference is that it binds to selective androgen receptors (AR) whereas steroids bind to all the AR. Andarine works by mimicking the features of Testosterone. Like testosterone, it does not work on the reproductive organ. Its actions are limited to bones and muscles. S-4 works by binding to the tissues of bones and muscles and increases your strength and lean muscle mass. It has one-third binding affinity of that of testosterone.

Andarine S4 – Legal or Illegal?

SARMS are legal as long as they are sold and bought as “research chemicals”. But Andarine is banned in sports and considered illegal if sold as dietary supplements.

 S-4 Clinical Case Studies

Case studies are obtained after tremendous research with these substances. It helps to understand the benefits and possible side effects of S-4.

Case Study 1

S-4 works as a complete Androgen receptor agonist for bones and muscle tissues. But when it comes to the prostate gland it works as a partial agonist. It helps in the increase of lean muscle mass without any side effects on the prostate. It provides complete bio-availability with a short half-life.

Case Study 2

S-4 helps in the increase of bone mineral density without any androgenic side effects. Postmenopausal women can use Andarine to treat osteoporosis without the risk of virilization.

Useful Effects of Andarine

Some benefits of Andarine S-4 are mentioned below:

• Increase in Muscle Mass – Most important reason for the popularity of S-4 is increased muscle mass. It causes rapid muscle gain along with fat loss.
• Increase in Bone Strength – Andarine helps to increase the bone mineral density and is used as a possible cure for osteoporosis. As it provides muscle strength too, it reduces the risk of falls and fractures in the bone.
• Weight Loss – Another reason why Andarine has such high ratings is that it helps you to lose all the extra fat from your body keeping your hard-gained muscles intact. You can lose up to 4-5% of body fat on the S4 cycle.
• Enhanced Recovery – Andarine helps in body recovery. After a hard-core gym session, it takes 72 hours for your body to recover completely. But on an S4 cycle, it comes down to 24 hours.

Possible Side Effects Of S4 (Andarine)

However note that the safety and full effect of this drug has not been tested on humans, only on rats and dogs. So the benefits and risks are fully unknown for certain.

From most unofficial reports the common side effects are:

• Suppression – It suppresses the normal production of testosterone in the body. Your natural level of Testosterone is returned a few weeks after the S4 cycle. Pure Andarine does not cause much harm to the testosterone level when you buy from real brands.
• Impaired Vision – Some people complain that when they are taking the compound their eyes become extra sensitive. Some even say that they notice a yellowy frame in their eyes. You should keep in mind that Andarine does not cause any permanent eye damage and these symptoms go away a few weeks after the cycle is over.

How To Use Andarine?

You should start S-4 or any other SARM with a low dosage and increase it accordingly. The dosage of 20-30 mg/ day five times a week is the most suitable dosage. This cycle should go on for 10-12 weeks. Anything more than this dosage might cause side effects like blurry vision and increased stress. But once again we draw your attention to the fact that there is no confirmed, safe dosage, since the drug has not passed any medical trials/received approval for human trials. Any dosage is from experienced users.

How To Stack Andarine S-4?

If you want Andarine S-4 to work then start taking them in stacks.

• Bulking Stack – Ostarine MK 2866 stacked with Andarine s-4 with a small dosage of Candarine  GW 501516 works like a miracle! These SARMS are useful in increasing strength as well as helps in both bulking and cutting. You should maintain the dosage of 20mg of Ostarine and Candarine per day with 20-30 mg of S-4.
• Cutting Stack – For cutting stacks, the combination of Andarine and Testolone RAD 140 is the best. Testolone gives immense strength while S-4 helps in fat loss. 10mg of RAD 140 and 25 mg of Andarine will do an amazing job.

Andarine S-4 Results

The results may be different depending on the quality of the product you buy, so opt for the high-quality drug. The best Andarine S-4 SARM results can be achieved at a lower dosage. You can see a vivid difference between before and after S4 SARMS, some of the are increased muscle strength, fit body, improved endurance e.t.c.

Due to high anabolic effects, you feel much more powerful and your workout times increase too.

Safety Measures While Taking Andarine S4

You should always start with a smaller dose at first. Preferably, 25 mg or even less of s4 supplements per day. Another thing you must do is regular Post –Cycle Therapy (PCT). This would ensure that your testosterone level gets back to normal after a cycle of S-4.

Final Thoughts

We hope that the article on andarine review was helpful and informative to you. While using SARMS you should always be careful and take the necessary precautions to avoid health hazards.

Just remember to consider your health, and if you have any more questions, feel free to ask them in the comment section!

The post Andarine (S4) Guide: Benefits & Side Effects of S4 SARMs appeared first on Sport Peptides.

Before you start using it, here’s everything you need to know about the HGH fragment 176-191:

What Is HGH Fragment 176-191?

HGH Frag 176-191 is a growth hormone that releases peptide fragment 176–191 that regulates fat metabolism to allow the body to burn fat. It stimulates lipolysis (the breakdown of fat) and blocks lipogenesis (conversion of non-food material into fat).

When combined with a workout, HGH fragment has been shown to increase the user’s ability to burn fat or lose weight. More studies on the supplement have shown an ability to boost IGF-1 levels, which offers the Fragment the power to induce anti-aging effects.

Is Frag 176-191 Effective?

After tests with real users, it has been established the Frag 176 191 comes with numerous verifiable benefits. Some users have experienced improved fat burning, and the hormone has also been linked with quick weight loss. It stimulates the breakdown of fats and increases energy, making it a safe choice for people looking to shed weight without taking a risky route.

Also, you will love that the hormone does not have an impact on insulin, so no glucose increases. It’s also useful if you want seamless muscle recovery.

Is Frag 176-191 Proven Scientifically?

The benefits of HGH Frag 176-191 were scientifically proven, showing that human GH is effective in treating obesity. A study involving obese mice showed a reduction in weight following chronic ip administration. These results correlate with a boost in the expression of beta(3)-AR RNA, a primary lipolytic receptor in fat cells. In humans, it has shown to effectively regulate metabolism without affecting insulin sensitivity, marking a significant milestone in the treatment of obesity.

Benefits of HGH Frag 176-191

The HGH Fragment was proved effective as a weight loss solution, but you can also draw more benefits from using the growth hormone. Here are some reasons you should include the product as a part of your lifestyle.

●   Boosts the ability to burn fat 

●   Does not increase glucose or insulin levels

●   Boosts energy levels  

●   Increases bone density      

●   Offers anti-aging benefits  

●   Stimulates lipolysis

●   Helps with weight loss       

●       Improves muscle recovery

Side Effects of HGH Frag 176-191

Using HGH also comes with possible side effects. These side effects could show with illicit forms or the prescribed version of the hormone. Both younger and older people can be affected. Some of the side effects include:

• Muscle, joint, or nerve pain
• Carpal tunnel syndrome
• High cholesterol levels
• Increased risk of diabetes and heart disease
•  Enlarged heart
• Tingling and numb skin
• Dependency, mood changes, and withdrawal
• Liver damage
• Enlarged breast in men
• Low blood sugar
• Fatigue

HGH Fragment 176-191 Dosage Guidelines

Pay attention! The dosage information provided is an average, so there could be variations from one individual to another based on special needs.

●       For a beginner:

200 mcg before breakfast

200 mcg 30 minutes before training

5 to 7 days a week of subcutaneous injections

●       For intermediate:

250mcg before breakfast

250mcg 30 minutes before training

About 5 to 7 days a week with subcutaneous injections

●       Advanced level:

200 mcg before breakfast

200 mcg before lunch

200 mcg 30 minutes before training

7 days of subcutaneous injections a week

If dosing multiple times a day, you should separate administration with at least 3 hours. These hgh doses for fat loss should work for the average person, but depending on one’s severity of weight gain, you’ll need a different dosage. You can pick from the three levels of dosage, also considering GHRP 2 vs GHRP 6 levels of the hormone.

Before taking it, however, make sure to consult the doctor for choosing the correct dosage and avoiding any side effects.

HGH Fragment Results from Confirmed Cases

To verify whether hgh fragment 176 191 reviews provide any real information, it’s important to look at real cases highlighting results. Many people that use GHG Fragment recorded satisfactory results. These include loss of fat deposits, especially around the stomach and waist area.

They also saw improvement in muscle bulk, which was even better for those who combined with appropriate exercise. Also, results from confirmed cases showed increased stamina, partly attributed to the development of leaner body composition. Other users reported enhanced endurance, a feeling of wellbeing, and stress resistance.

Recommended Food Pairings with HGH 176-191

For the best results, you should take hgh 176 191 separately from food. You can only take it with only protein in your stomach or on an empty stomach, so fasting is a great help here. When the growth hormone hits its peak, then you can consume anything you want.

For the morning injection, you should inject as the first thing in the morning, followed by some cardio exercise, then a few hours of rest before taking breakfast. Ensure your first meal is predominantly protein, low in carbohydrates, and low in fats.

For nighttime injections, you can inject the growth hormone after your last meal. It should contain mostly protein, low in carbs, and low in fat. Following these routines helps your body make the best use of the hormone’s fat-burning effects, leading to significant fat loss.

Dietary Recommendations

The recommended diet for the best results using HGH Fragment should be heavy on proteins, low on fats, and low on carbs. This creates the best conditions for the hormone to act and stimulate the fat-burning process.To lose fat, you need to create a caloric deficit. This means eating less calories compared to the energy your body expends, so the body switches to burning stored fat for energy. For men, the recommended deficit is 2500 to 3000 calories and for women it is about 1500 to 2000 calories.

Verdict and Our Recommendation

Research has proved the effectiveness of HGH Fragment in assisting through weight loss. It stimulates the breakdown of fats, offers anti-aging benefits, and is a good product for anyone looking to lose weight. When you use the best HGH Fragment 176-191 2020, just ensure you adhere to diet recommendations for the best results.

The post HGH Fragment 176-191: Dosage and Results of HGH Frag appeared first on Sport Peptides.

What is LGD-4033? 

It is also called Anabolicum LGD 4033. In a short period, it has become one of the most common SARMs due to its powerful effects. LGD-4033 is found in three different forms: liquid SARMs, powder, and capsules. Take note that LGD 4033 is not a steroid; however, the FDA has classified it as an illegitimate substance. Thus it’s illegal to sell it as an ingredient in supplements. FGD 4033 has numerous advantages on body recomposition, sex drive, and muscle building.   

How Does Ligandrol Work?

LGD 4033 is anabolic; it’s not converted to estrogen, neither is it androgenic. However, it works with androgenic receptors, thus does not affect any vital body organs such as the lungs, heart, or kidney. LGD 4033 effectively aids in body fat loss; it one of the best SARMs for cutting. It promotes lean muscle growth and strength. Ligandrol is used in treating muscle weakness and wasting, which is a symptom of cancer.    

LGD 4033 Benefits

Ligandrol LGD-4033 has several benefits to the body. Some of which include:

• Increased Muscle Strength – Muscle growth comes with a flow of strength. You get more power to work out for more extended periods. 
• Lean Muscle Growth – As aforementioned, it’s one of the critical benefits of LGD SARM. It works combine with androgen receptors in the muscles and bones for muscle regeneration. In one cycle length of LGD 4033, you can gain about 8 to 13lbs of muscle mass.
• Maintain Muscle Mass – After you have attained your desired muscle mass, maintaining it is equally important. LGD 4033 comes in handy on this. It ensures you burn enough fat in this phase and prevents loss of muscles.
• Enhances Muscle Recovery – In bodybuilding, muscle recovery is essential after training hard. Usually, your muscle experiences wear and tear during workouts then naturally rebuilds back; this process makes them stronger, thus giving you strength. LGD 4033 promotes rapid muscle recovery.    

LGD 4033 Common Uses

If you have read most SARMs reviews, you’ll agree that LGD 4033 is an essential supplement with several benefits, as mentioned above. Here are some of its common uses:     

For Bodybuilding

Most bodybuilders use LGD-04033 capsules to increase muscle mass and also reduce muscle wasting within the body. LGD 4033 liquid is also popular with bodybuilders and among the strongest on the market.     

For Bulking 

Bulking refers to the intentional increase of calorie intake, beyond body requirement, combined with an intense workout to achieve the desired body mass. There is evidence that LGD 4033 increases bone strength and density. This helps prevent any health issues or muscle strain during bulking.     

For Cutting 

Cutting refers to shedding excess body fat building lean muscle. LGD 4033, if combined with Candarine, forms a suitable stack for cutting. Ligandrol reviews suggest taking it with low-calorie meals    

How to Take LGD-4033?

LGD 4033 has a half-life of about 30 hours. You can maintain an increased anabolic effect with a single dose a day. It is administered orally once a day, preferably in the morning after night fast. It is recommended that you start with small amounts as you monitor your body reaction. Take note that LGD 4033 has not passed all clinical tests and has not been approved by the FDA, so take it at your own risk and preferably consult with your doctor.

LGD-4033 (Lygandrol) Commercial Forms

As of today, you can buy LGD-4033 in the different commercial forms. For example, you can buy drops and tablets from various manufacturers. At the Chemical Book, we found 74 suppliers and manufacturers, and we recommend you to check your national providers carefully, or buy SARMs and peptides from trusted national manufacturers only.

LGD 4033 Dosage  

It is advised that LGD 4033 for women be taken in small doses, 5mg/day

The dosage of this drug varies depending on your fitness purposes. For recomposition, take 5-8mg for 8 weeks. For bulking, combine it with Ostarine MK 2866, whereas for cutting, combine it with Candarine.

LGD 4033 Cycle

LGD 4033 has a cycle of about 6 to 8 weeks. It’s recommended to start at a low dosage, 5mg, for a minimum of 6 weeks. Don’t expect results within the first two weeks; you have to be patient. Experienced users can increase the cycle to 8 to 10 weeks with a moderate dosage, 5-10mg. After the cycles, you may be required to use PCT. This helps you recover and avoid losing gains.  

Stacking LGD-4033

Most users stack SARMs to get better results; LGD 4033 is no exception. Stacking two or more SARMs provides the benefits of both, which yields faster and better results than using a single SARMs. 

There are two types of stacking:

• Bulking stack – Combine LGD 4033, Ostarine MK 2866, and Candarine. All these are good for bulking and have good strength. Taking 20mg of Candarine and Ostarine, and 10mg of Ligandrol per day will yield the best results.
• Cutting stack – A combination of Anabolicum and Candarine GW501516 is a perfect stack for cutting. Also, take a low-calorie diet for faster results.

Post Cycle Therapy

After completing a SARMs cycle, you may experience some side effects or withdrawal symptoms. This is where PCT comes in. Taking a mild PCT is beneficial in muscle recovery, curing, and preventing side effects.

Ligandrol Side Effects

LGD 4033 should be taken in moderation. The most common side effects include fatigue, headaches, nausea, and water retention. It may lead to decreased testosterone. Research also shows that this drug can increase liver stress. Remember to hydrate. More so, after completing a cycle, immediately start a PCT to prevent side effects.

Conclusion

LGD 4033 is well known for its treatment of muscle wasting. However, in bodybuilding, it’s used for enhancing muscle growth and maintaining lean muscle.  Take note that taking LGD 4033 in moderate doses can be really beneficial. You achieve perfect results if you also take it with a healthy diet and regular workout. On the other hand, excessive dosage may lead to severe side effects. However remember that it has not been approved by the FDA, so be really careful with how you use it! You can check our LGD 4033 reviews 2020, if need more information before making that choice. 

We hope you have all the much-needed knowledge to get the body you desire while staying healthy!

The post LGD 4033 (Ligandrol) SARM Review: Benefits, Side Effects, Dosage and PCT appeared first on Sport Peptides.

The good news is that you don’t have to spend hours reading all the scientific texts, trying to figure out what to do. We have talked with experienced bodybuilders, fitness, and health professionals to gather all the information to bring you some peptides reviews.

What Are Peptides?

In short, peptides are a small variety of proteins.  When you observe a peptide, you realize that it is a string of amino acids, only shorter.  It contains between  2 and 50 amino acids, whereas a protein contains more. They are created naturally and exist in all living organisms. Peptide’s role in biological activity is crucial. The function of a specific peptide depends on the type and the sequence of amino acids in the chain. They often act as hormones and thus carry relevant information through blood, from one tissue to another. 

How Do Peptides Work?

So how are these muscle growth, fat burning peptides function?  Peptides are used for muscle gain, weight loss, recovery, decreased inflammation, skin health, etc.  There are a lot of peptides, and they target different parts of the body. For example, some peptides play a role in enhancing the production of Growth Hormone, produced by the Pituitary Gland.  This hormone is not responsible only for growth but also for general body regulation, proper functioning of the GI tract, and insulin levels.

Are Peptides Legal?

Before deciding whether you want to use peptides or not, we have to talk about legality. Of course, this is something that depends on the country where you live. For example, in Australia, you can buy them but with a prescription from your doctor. In the USA, for the time being, it is illegal to buy peptides, unless you want to use them for research. The reason for that is because these supplements are considered powerful drugs that may have adverse effects.

Are Peptides Steroids?

No, they are not. The simplest way to explain the difference between peptides vs steroids is to say that steroids are synthetic, whereas peptides are perfectly natural.  They use natural codes to send other cells a message on what they should do – for example, the best peptides for fat loss tell other cells to burn fat for energy and not sugar. However, the same as steroids they are classified as performance-enhancing drugs.

Peptides Benefits

• Increased energy
• Fat loss
• Increased lean muscle mass
• Improved performance
• Improved recovery time
•  Increased strength

Peptides Side Effects

• Increased hunger
• Itchiness  in the injection area
• Tingling and numbness

Types of Peptides

• Ipamorelin (CJC-1295)  

This is one of the newest on the market, and it is already considered one of the best peptides for muscle growth. It is a combination of two peptides, and it is quite efficient in stimulating the pituitary gland to release GH. If you decide to take it, the best is to inject it at night to maximize the natural growth cycle. The good thing about it is that it won’t increase your appetite.

Dosage

Start with 100 mcg and gradually increase to 200 mcg. The best effect is achieved when it is combined with 100 mcg GRF-MOD1 29. Take it for 8 to 12 weeks.

• BPC – 157

Okay, so BPC  – 157 is a fragment of protein BPC that is found in the stomach acid. It is one of the top peptides that enhance muscle and tendon healing. It is sought after because of its regenerative potential and ability to heal wounds, cuts, etc.

Dosage

There are no peer-reviewed clinical trials for this drug, thus there is no information about dosage. While conducting tests on mice and rats, scientists use ten nanograms up to ten micrograms per kilogram. It is equivalent to 600mcg for an adult human who weighs 60kg.

• GHRP-6

The main reason why this growth hormone is in such demand is its incredible capacity to increase the size. It is also used for weight loss and anti-aging.  It stimulates the release of ghrelin, an enzyme that enhances the appetite. This is the reason why bodybuilders that are struggling to meet their calorie needs take it.

Dosage

It is advised that you take one mcg /kg per day (once in the morning and once in the night). You shouldn’t take more than 300 mcg per day.

• GHRP – 2

This one is used for the same reasons as the previous one, but it is stronger. The difference is that this  GHRP –  doesn’t make you as hungry as GHRP – 6, which is why it is maybe useful as the best peptide for female fat loss. It is also preferred by people who want to have lean muscle mass.

Dosage

You can take it in the same way as GHRP -6. For optimum results, you can combine two peptides.

• Bremelanotide (PT-141)

PT-141 recently got a lot of attention because it turns out to have potential in healing and recovery from physical injuries as well as hemorrhagic shock. Some studies indicate that it is efficient in treating low libido and sexual dysfunction as well. But this counts only for men.

Dosage

It is administered through an injection or nasal atomizer. Check this review to get more info about PT-141.

• TB-500     

It is a synthetic part of the protein thymosin beta  – 4, which exists in all humans and animals (here you can find more info). Its main role is to promote healing,  but tb-500 plays a part in the creation of new blood and muscle cells. Its healing properties have been seen in tendons, ligaments, muscle, skin, heart, and eyes. 

Dosage

Mix one milliliter of water with powder and inject.

• Insulin-like Growth Factor-1 (IGF-1)   

This type of product is good to use when you want to target one specific group of muscles. In the past years, it became one of the most popular peptides for muscle growth.  It has anabolic effects in adults.

Dosage

It is recommended that men take 40 -50 mcg of IGF – 1 daily. Women shouldn’t take more than 20mcg.

How to Inject Peptides

Injecting peptides is quite easy. The critical thing you need to know is that the needle should enter subcutaneously – very little under the surface of the skin. Here are the best places to inject.

• Upper arm
• Abdomen
• Thighs
• Lower back

Instructions:

1. Wash your hands
2. Prepare the needle and the powder.
3. Clean the place where you will inject
4. Take 1- inches of the skin between thumb and forefinger.
5. Insert the needle
6. Let the skin and press the syringe plunger.
7. Take out the needle
8. Apply pressure to the place of injection.

Concluding Remarks

Here we are, at end of our review of best peptides  2020. As you can see, there are many options and many factors to consider. Although peptides are generally safe for healthy people, we would advise you to consult your GP before taking them.

The post 7 Best Peptides for Weight Loss, Muscle Growth & Bodybuilding appeared first on Sport Peptides.

Before we get started, a word of warning – this is a substance banned by the World Anti-Doping Agency, so do not use it if you’re participating in professional sport!

What is TB-500?

If you have acute pain which needs alleviating, one of the best options is to periodically inject a TB-500 dose. The substance is a synthetic thymosin beta 4 peptide that will help you quickly heal from wounds, bodily pain, or muscle damage. In particular, it has gained notoriety for its repair of muscle, tendons, heart, skin, and eye injuries. The synthetic compound is much related to its parent beta 4, performing the same sort of task in the body, but thymosin beta4 is not as easily produced due to its size. The TB-500 peptide is a preferable option because it can be easily manufactured.

The uses of this peptide are broad and can be used in the following:

●     Repair of soft tissue

●     Healing from athletic injury

●     Ligament, tendon or muscle repair

●     Treatment of Multiple Sclerosis

●     Treatment of spinal cord injury

●     Treatment of eye disorders

●     Improvement of immune support

●     Use in the repair of chemical burns

●     Reducing inflammation

Thymosin Beta: A Brief Overview

There is a lot of information online about different peptides, with claims that they can cure a number of ailments. You may have read discussions on the likes of topics such as tb 500 vs bpc 157: so what is thymosin beta? In short, it’s a protein encoded by the TMSB4X gene in humans consisting of 43 amino acids, with the following sequence:

SDKPDMAEI EKFDKSKLKK TETQEKNPLP SKETIEQEKQ AGES

You can find this protein in all bodily tissues and cells, with the exception of red blood cells. What’s so important about this protein is that scientists regard it as the main G-actin sequestering peptide, actin being the most abundant protein found in our cells. Thymosin beta is also angiogenic, promoting the growth of vasculature in the body. 

Thymosin beta 4 benefits the body by promoting adhesion, cell migration, cell proliferation, wound healing, scarring healing and it reduces inflammation.

How Does TB-500 Work?

Tb-500 and thymosin work by upregulating the proteins that build bodily cells, primarily actin, a protein that forms muscle cell filaments and is involved in the metabolism of numerous cells. Actin is a cellular protein critical to cell mobility, muscular contraction, and signaling between cells. Upregulation results in improved cell growth, healing, cell proliferation, and cell migration. Studies from Wei et al. show that the peptide can even reduce pulmonary hypertension and hypertrophy in the heart.

The substance increases angiogenesis (blood vessel formation) around damaged tissues, expanding new blood vessel pathways and reducing inflammation – all of this results in faster wound healing. When you research and read peptides reviews online, you’ll notice the thing that sets Tb-500 apart is its low molecular weight. This allows it to travel long distances through bodily tissues, targeting injured areas much quicker and easier than many other peptides.

TB-500 Benefits

If you’re wondering “what does thymosin do?”, there are a wide range of benefits documented in scientific research:

●     An improved cell migration towards the site of injury – tb-500 results in an increase of cell migration around the body, helping the body repair its tissues quickly and effectively.

●     Reduces inflammation – a study by Sosne et al. found that the compound is a novel anti-inflammatory agent, producing a diverse array of healing properties. The research has also found that the substance can suppress apoptosis.

●     Reduction in pressure ulcers – double-blind clinical trials have found the substance can reduce the intensity of pressure ulcers when administered topically.

●     Greater endurance – because wounds heal faster and inflammation decreases, people feel healthier and have greater endurance. This is especially noted among athletes.

●     Brain function recovery – studies found in the National Library of Medicine link thymosin beta-4 and related peptides to the reduction of brain injury. The anti-inflammatory properties of thymosin reduce traumatic brain injury and promote angiogenesis.

●     Promotes wound healing –  tb 500 creates an expression of matrix metalloproteinases. These can lead to increased wound healing in muscles all around the body.

How to Use TB-500?

When looking at peptides reviews, you’ll find that tb 500 is most commonly administered with an injection into the body. The process is relatively simple and effective – all you need to do is determine the correct dosage, gather required materials, and follow basic steps to inject correctly.

Dosage and Cycle Duration

You calculate TB-500 dosage based on the damage or injury sustained to your body, and people normally use between 4 – 8 mg of the substance on a weekly basis during an initial “loading phase”. After this, you can keep taking the substance indefinitely every two weeks for as long as you need to. Usually, the effects are known to wear off around 2 weeks after injection.

The correct tb 500 dosage for humans is based on weight. For a 90kg person, the recommended dose is 7.66 mg per week for a six week period. You can derive this by calculating using a formula, based on greyhound doses, according to MediVet (a company producing tb 500) and common scientific practices.

Human equivalent dose (mg / kg = Animal dose mg / kg) × (Weight_Animal [kg]/Weight_human [kg])

How to Mix TB 500?

Supplier peptide websites often sell TB-500 in a powdered form, and you can often find it commonly marketed under the name of Thymosin Beta 4. You need to mix the constituted powder with bacteriostatic water. Once you draw the mix into an insulin syringe, you can inject it how you see fit, either subcutaneously, intramuscularly, or intravenously. It’s a relatively simple process, condensed into three simple steps.

Supplies Needed For Injection

Relatively few supplies are needed, but do make sure you have the following:

●     Your TB-500 powder

●     Insulin syringe

●     Bacteriostatic water

●     Alcohol-based swab

Bacteriostatic water is a must here – you can’t use ordinary water from the tap. The process needs to be kept as sterile and clinical as possible to avoid any possible risks of contamination or infection.

Mixing TB-500: A Step-by-Step Guide

1. Remove the lids from your containers of water and powder.
2. Clean both the rubber stopper of the TB-500 container and the top of the bacteriostatic water vial with your alcohol swab, then wait till the alcohol dries off completely before proceeding to the next step.
3. Fill your syringe up with water, slowly injecting it into your TB-500 bottle. Let it slide down the sides of your container and avoid spraying directly onto the powder. Take your time with it and don’t rush or you could damage the powder itself. You will need to repeat this process around three times to fill up the whole bottle.

The process is now complete. If it sits at room temperature or has direct exposure to sunlight then it will go bad. Keep the substance in your freezer or refrigerator to preserve it before use.

How to Inject TB-500

There are three main ways of injecting TB-500. Before engaging in injection, double-check that you’ve cleaned the container with your swab to ensure minimal contamination.

Intramuscular injection – the most difficult of methods. You will need to stab your muscle as close to where the injury occurs. The needle needs to be inserted further than under the skin, so a stabbing motion is required here.

Subcutaneous infection – an easier method whereby you pinch the area of skin and push your needle through. Make sure you inject as close to the injury as you can.

Intravenous injection – your needle is inserted into a vein, commonly one that’s near your elbow, wrist or the back of your hand. It can be a tough method, especially for first-timers. We would recommend getting medical supervision with this method.

After injection, massaging the area will help the substance kick into the tissues, improving the effectiveness and absorption by the body.

Tb 500 side effects and risks

There are relatively few tb-500 side effects, but it is essential to take note of recent studies that have found a link between thymosin and cancer. Studies carried out by Zhang et al. show a link between thymosin and cancer cell growth, increasing the likelihood of pancreatic cancer in particular.

However, research into thymosin beta 4 side effects and cancer is disputed in academia. Doctors initially found higher amounts of thymosin in cancerous tissues and assumed that thymosin beta 4 results in cancer cell production, but many believe that its presence is instead a result of increased white blood cell production. The presence of this substance may therefore indicate higher white blood cell growth as opposed to an increase in cancerous tissues. Circumstantial evidence also points to feelings of lethargy after injecting the drug, but this is yet to be widely documented in the scientific literature.

How to Store TB-500?

Make sure that you store your peptide powder and reconstituted TB 500 between a temperature of 36 and 46°F. Under this temperature, a typical vial of un-constituted substance can last for two years, but a temperature of 98°F can also work well for around 90 days of storage. Once you reconstitute the parlor, it should be used within eight days and you do not want to freeze the peptide at any point.

Conclusion

With all the best peptides available online, there is a lot of conclusive evidence around TB 500 and bodily repair. We hope you’ll take away some of the facts we’ve presented so that you know exactly what to look for. There are several different uses for TB-500, most notably in repairing bodily tissue, helping to reduce muscle damage, and rid the body of inflammation. It is an exciting substance that offers promise for those who suffer from pain and damaged tissue. The future’s bright and a wide range of new clinical applications are being investigated other than using TB-500 for muscle growth, including the use of TB-500 in repairing the spinal cord and bones. The substance is even being considered for the treatment of aging, viral infections, kidney disease, and liver failure. 

Who knows what exciting TB-500 technologies will be developed soon. Make sure you keep on top of all TB-500 reviews 2020 has to offer and best of luck in your research.

Article compiled using information from the following sources:

1. https://en.wikipedia.org/wiki/Thymosin_beta-4
2. https://a4m.com/assets/pdf/covid-19-resources/Thymosin%20beta%204%20prof%20monograph.pdf
3. https://pubmed.ncbi.nlm.nih.gov/2677145/
4. https://pubmed.ncbi.nlm.nih.gov/26096726/
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804402/
6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930015/
7. https://pubmed.ncbi.nlm.nih.gov/26096726/
8. https://zenodo.org/record/1230768#.XZZJPfxKgUs
9. https://www.jbc.org/content/early/2014/05/14/jbc.M113.529966.full.pdf
10. https://pubmed.ncbi.nlm.nih.gov/25412097/
11. https://www.clinicaltrials.gov/ct2/show/NCT00382174
12. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701135/
13. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547647/

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What is PT-141?

PT-141 is a peptide hormone treatment that is mainly innovative for improving sexual function in both men and women. It is a derivative for Melanotan II, more specifically a synthetic cyclic heptapeptide derivative of the alpha-MSH hormone. Its chemical makeup means that it works as a non-selective agonist for receptors MC1 to MC5, which are found primarily in the body’s nervous system. 

You may have heard it more commonly referred to as Vyleesi, Bremelanotide, or the “sex peptide” as it produces a positive sexual response. Other than the enhancement of sexual libido, consumers can also benefit from enhanced energy levels and greater arousal. 

As for the question “Is pt 141 legal?” – after many years of research and clinical trials, the peptide was finally approved by the FDA in 2016, as a treatment for sexual dysfunction in premenopausal females.

PT 141 Background

Initially, peptide pt-141 made its way into research as a possible tanning agent for UV-free or “sunless” tanning. By applying this agent, it was thought that the application could produce the effect of a tan on the body, commonly referred to as a fake tan. Melanotan II tests revealed some darkening pigmentation but also led to a heightened state of sexual arousal and spontaneous erections in many male volunteers. There was a dawning realization, that pt-141 peptide could contribute better as a treatment for sexual disorders, particularly erectile dysfunction in men and a lack of sexual arousal in women. This became especially apparent after a leading scientist self-experimented on themselves, injecting the compound into their body. As a result, they had an erection for eight hours. However, it wasn’t until many years later that the drug got approval from the FDA as initially there were discrepancies regarding elevated blood pressure and trials had to be postponed.

Both Hypoactive Sexual Desire Disorder (HSSD) and Inhibited Sexual Desire (IDS) are considered sexual dysfunctions that lead to both an absence of sexual fantasy or sexual desire. In particular, Female Sexual Arousal Disorder (FSAD) renders women unable to maintain arousal or even attain sexual arousal during periods of sexual activity. 

Pt-141 acts as a synthetic manmade aphrodisiac and is unlike many other related PDE5 inhibitor medicines such as Cialis and Viagra. The interesting thing about Pt 141 is that it doesn’t act upon the vascular system, rather it works directly on the hypothalamus in the brain to increase feelings of desire. Common medicines such as Viagra or Levitra aren’t aphrodisiacs and have no effect on a person’s libido, yet when used in combination with Pt-141 they are known to produce a synergistic effect.

Who Is This Peptide For?

If you look at peptides reviews online, you’ll likely notice that most people using this substance are those who experience some degree of failing sexual health. This peptide is particularly for those who have troubles with sexual dysfunction. Unlike a lot of other common sex substances, this substance is for both men and women.

How Does It Work?

Pt-141 for men and women works on the nervous system, increasing satisfaction, desire, and sexual arousal. Unlike other treatments that work on the vascular system and only give one the ability to maintain an erection, this substance creates motivation and desire along with an erection. It works just as well in females as males too, helping to boost libido. 

The result is that consumers can enjoy the passion and intimacy of their relationships. In some essence they are the best peptides for sexual health because they work on the nervous system and do not affect cardiovascular health – this makes them safe for a diverse population, including those who are prone to heart conditions.

The peptide stimulates the production of dopamine hormones which increase sexual motivation. Dopamine is a common neurotransmitter that is responsible for performance – when you don’t produce enough of it, you can feel depressed and have a low libido in general. While pt 141 works to boost sexual health, it can also be great for increasing natural energy levels without resorting to harmful means such as drinks or pills. Moreover, the effects of pt 141 make it a great option as a fake tan, helping people get darker skin much faster than with conventional tanning methods.

PT 141 Benefits: Scientific Evidence

Even though there are plenty of positive peptides reviews online, it is important to consider the scientific evidence when taking substances for yourself. Studies on bremelanotide pt-141 in journals such as Nature reveal conclusive evidence of pt 141 nasal spray increasing erectile response. This study conducted in healthy male participants showed a statistically significant increase in erectile response when compared to a placebo, with an erection occurring after 30 minutes. Similarly, a 2003 study by Molinoff et al. found that an administration of pt 141 to patients experiencing erectile dysfunction created a rapid increase in erectile activity, holding “promise as a new treatment for sexual dysfunction.” Results such as these have been echoed in double-blind trials of the substance on healthy humans.

General Benefits  

Although key studies such as those by Clayton et al indicate the peptide’s use for combating sexual health problems, there are all sorts of other benefits to pt-141 intake. 

There are even benefits unrelated to sexual health:

●     Anti-cancer properties – the MC-1R receptor works as a stimulus in DNA pathway repair. For this reason, scientists see potential in its future as a cancer treatment.

●     Anti-inflammatory properties – research has found MC-1R to harbor a number of important anti-inflammatory properties. Current research is underway, investigating the substance’s future as a fungal infection treatment.

●     Tanned skin – initially the substance was investigated as a tanning agent. One can apply pt-141 superficially to heighten the appearance of tanning.

●     Promotes skin tanning – on top of a superficial application, the peptide can create a darkening of skin pigmentation when injected into the body.

●     Increase in energy levels – early trials of pt141 concluded that it increases people’s energy levels. 

Extra Benefits For Men

Many effects of bremelanotide for men have been well documented:

●     Treatment of erectile dysfunction – The substance creates erections for men, helping to cure premature ejaculation, as well as impotence.

●     More frequent erections – males experience more frequent erections. Erections also last a lot longer, between 2-6 hours on average. Double-blind trials found that the substance is effective in treating sexual dysfunction, erectile dysfunction, impotence, and premature ejaculation.

●     General health benefits – this substance is much less likely to lead to heart attacks or strokes compared to other medications such as Viagra.

Extra Benefits For Women 

Looking at numerous pt 141 women’s reviews you’ll see that the benefits aren’t only for men, they are for women too. The research found in scientific literature, including a multidisciplinary review by the FDA, outlines some benefits to females:

●     Treatment of generalized hypoactive sexual desire disorder – this is by far the largest benefit to women. More blood flows to the sexual organs and consumers note feelings of greater libido, as well as more pleasurable sexual activity.

●     Vasocongestion – sexual arousal, menstruation and several different factors can create vasocongestion in humans. Pt 141 can be used as a treatment.

●     Pelvic floor strength – one side effect of peptide 141 is that it creates a strengthening of the pelvic floor, working wonders for general female health.

Using PT-141              

There are numerous ways to take the peptide compound, such as sprays or direct injections. Usually, doctors recommend taking a dose 45 minutes before sexual intercourse. The FDA recommends that consumers should not exceed one dose per 24 hours or 8 doses a month. If no improvement in sexual libido or arousal is achieved after an 8 week period of use, you should consult a doctor.

PT-141 Dosage

● Bremelanotide is most effective when applying as a 2mg spray up each nostril.

● According to a 2016 study, the appropriate dosage for women is between 1.25mg and 1.75mg when used as an injection.

● Dosage can be adjusted if necessary, increasing dosage to 4mg, with two sprays per nostril.

● It’s important to consult a doctor or health practitioner to advise you on your recommended dosage. Dosage can vary depending on a person’s individual medical condition and sexual needs.

PT-141 Results

Every individual is different, but in general, the effects are felt within 30 minutes to two hours. Although administering the peptide can be an uncomfortable process, most men describe having long-lasting erections of up to 6 hours. After appropriate pt-141 dosing, both women and men can feel the effects for even up to 24 hours.

PT-141 Side Effects

Although the most noticeable effects of pt 141 peptide are on the sexual organs, there are a few common side effects. We recommend discussing all possible side effects with your doctor, as well as any underlying health conditions that could affect the dosage. When people dose too high, they most often experience headaches, although these are usually much less intense than with those taking other medications such as Viagra or Cialis.

The most common side effects include:

●     An increase in sexual arousal

●     Increased libido

●     A longer-lasting erection

●     Headaches

●     Vomiting

●     Flushing in the face

●     Skin pigmentation

●     Nausea

●     Coughing

●     Congestion in the upper nasal passage

●     An increase in male blood pressure

●     A decrease in heart rate

●     Irritation or itchiness around the injection site

PT 141: Overall Pros and Cons       

Conclusion

The FDA has approved pt 141 for men and women, helping to treat hypoactive sexual desire disorder as well as erectile dysfunction. Although there is current approval for females, it should be noted that the FDA has yet to approve the treatment for men. Still, a number of studies indicate its effectiveness in curing male sexual ailments. 

The future looks bright for this substance, plus you only need to look at the number of positive pt-141 reviews online that speak of its effectiveness. After doing your own research and reading all the pt 141 reviews 2020, always be sure to consult your doctor or healthcare provider regarding the correct dosage for pt 141, especially if you:

●     Have issues with your kidneys and/or liver

●     Are pregnant

●     Hypertensive

●     Have a family history of cardiovascular disease

●     Have high blood pressure

Compiled using information from the following sources:

1. https://www.fda.gov/news-events/press-announcements/fda-approves-new-treatment-hypoactive-sexual-desire-disorder-premenopausal-women
2. https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshots-vyleesi
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384512
4. https://www.nature.com/articles/3901139
5. https://pubmed.ncbi.nlm.nih.gov/12851303/
6. https://pubmed.ncbi.nlm.nih.gov/14963471/
7. https://pubmed.ncbi.nlm.nih.gov/18206919/
8. http://www.cnn.com/HEALTH/men/9906/17/viagra.alternative/
9. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/210557Orig1s000MultidisciplineR.pdf

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SARMs refers to the drug that works by binding to the androgen receptors of the body. A regular dose of SARMs paired with active gym sessions helps in the development of muscle mass and promotes the loss of body fat.

The results vary for different persons and depend on lots of factors: workout routine, genetics, diet, nutrition, and more. If you are about to commence on a cycle of SARMs dosage for burning body fat and gaining muscle mass then read the SARMs before and after a guide to know more about SARMs results.

What kind of body alterations should you expect after SARMs intake?

The regular dose produces the following SARMs before and after results in the body:

• Enhances muscular growth. The regular intake of the steroid for a few months results in a dramatic increase in muscle mass. The prescribed intake of SARMs over at least four months results in a gain in lean muscle mass for up to 30 pounds.
• Loss of excess body fat. Regular intake helps in the disintegration of body fat and the generation of energy.
• Noticeable stamina improvement stamina. Athletes can develop a high level of stamina by the intake of prescribed doses of SARMs. Drugs like Andarine and Testolone are especially recommended for the development of muscular strength and stamina.
• Faster recovery from muscle injuries. The intake of SARMs regularly helps in accelerating the recovery process and heals muscle pains and injuries faster. 

Results of Ostarine (MK2866)

Ostarine SARM is ideal for individuals who seek to develop a slim but muscular physique. For ostarine before and after usage, the user develops lean muscle mass of around 5-8 pounds in only one SARM cycle.

The intake of ostarine results in the retention of nitrogen that helps in developing the strength of the muscles. It also helps in the stimulation of connective tissues and muscle stem cells to enable faster recovery from the workout stress. Even though Ostarine is not as powerful as the other SARM drugs, it’s still highly effective for developing bone density, improving insulin resistance, and more.

Effects of Testolone (RAD-140)

Testolone is new to the family of SARMs and is one of the most powerful drugs as well. It’s administered for the development of muscle mass in patients with muscle degenerative disorders.

Observed rad 140 results include improvement of physical energy levels as well as improved stamina and endurance. The intake of Testolone throughout a 60-day cycle can help in the gain of muscle mass by 10-20 pounds depending on the type of workout routine of the individual.

Results of Andarine (S4)

First in the line of SARMs – Andarine, or S4, is perfect for boosting workout performance. Its regular intake makes the individual faster and stronger thereby intensifying his workout routine. It makes the muscles appear hard and strong at the second or third week of the intake cycle.

The prescribed intake of S4 helps in shedding the most stubborn fat deposits while building muscles at the same time. Physicians warn against the overdose of Aldarine and recommend Post Cycle Therapy as well.

Effects of Cardarine (GW 501516)

Cardarine is not exactly a SARM. It is a PPAR-delta receptor agonist. Some of the observed cardarine results are shed off excess fat and development of the energy levels of the body. Apart from boosting the workout performance, Cardarine also aids in maintaining a better body shape, contributes to cardiac health, and promotes healthy renal functioning as well.

What are the results of YK11?

The intake of YK11 helps in muscle growth and develops physical strength and stamina. It induces a high level of endurance and improves the workout performance of the user. Users who take YK11 regularly report less fatigue, quick recovery from muscle spasms, and toning of the muscles of the back and abdomen. The result of YK11 is faster and more prominent compared to the other SARMs.

Effects of Ibutamoren (MK 677)

Ibutamoren varies slightly from the other SARMs. It improves hormonal balance and helps in the development of lean muscle mass. The regular intake of Ibutamoren lowers fat mass, improves muscle power and endurance, and boosts the oxygen levels of the body.

MK 677 is highly popular among athletes as it is remarkably effective in burning fat and developing muscle mass simultaneously. However, when it comes to quicken the process of recovery from muscle pain and injuries mk677 is not as effective as other SARMs 

FAQs About SARMs

• How long will it take before you notice the results from SARMs?

The effect of the intake takes about four months to manifest in the form of rock hard muscles and abs.

• Can SARMs have any impact on your balls?

The intake does not have as drastic an effect on the balls as androgenic steroids. However, in some users, it can reduce testosterone levels and have other effects.

• Do you lose gains after SARMs?

One does lose the gains after SARMs.

• How long do SARMs remain in the system?

Most of the varieties of SARMs stay in the system for about two weeks or so.

Conclusion

If you seek to gain in muscle mass and improve strength and stamina, then the selective androgen receptor modulators are the best choice. The long term intake can contribute significantly to muscle mass when complemented with regular workout sessions. The SARMs transformation manifests as a lean but muscular look in athletes. Now that you have an idea about SARMs from the SARMs before and after guide, make sure to consult your doctor before taking this wonder drug, to be safe and gain only positive effects!

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